Marta Giovanetti

Marta Giovanetti

Marta Giovanetti research focuses on investigating the patterns of gene flow in pathogen populations, focusing in phylogenetics and phylogeography as tools to recreate and understand the
determinants of viral outbreaks and how this information can be translated into public policy recommendations. More specifically, her research focuses on recent arboviral outbreaks in Latin
America (Zika, chikungunya, dengue and yellow fever viruses), combining genetic, spatial and ecological information. She is interested in the epidemiology and ecology of viruses in natural
populations. Her research involves developing and applying techniques to integrate virus genetic data with traditional clinical and demographic data.
After completing her PhD in molecular evolution of RNA viruses and performing field work in Sierra Leone with Ebola virus, I started a postdoctoral position in the Laboratory of Prof. Luiz
Carlos Junior Alcântara at the Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Brazil, investigating the evolution of arthropod-borne viruses such as Zika, Chikungunya and yellow
fever virus. She is currently a Visitant Researcher at the National Reference Laboratory of Flavivirus in the Oswaldo Cruz Institute in the Fundação Oswaldo Cruz in Rio de Janeiro,
Brazil under the supervision of Dr Luiz Carlos Junior Alncantara and Dr Ana Maria Bispo de Filippis, working with the ZiBRA project (Zika in Brazil real-time analysis, www.zibraproject.org), a project that aims to improve genomic surveillance of emergent and reemergent RNA viruses circulating in Brazil. We built upon recent methodological advances in virus nanopore sequencing (e.g. Faria et al., 2017, Nature; Quick et al., 2016, Nature; Faria et al., Science 2018), that gave us the possibility to generate >200 Zika virus genomes from different geographic regions in Brazil, >400 Yellow Fever genomes from the recent outbreak in Minas Gerais, Bahia, Rio de Janeiro, Espirito Santo and Sao Paulo, and >150 Chikungunya virus genomes from the Northeast, Southeast and North regions of Brazil. Her research focuses on generating these genomes in real-time using nanopore sequencing technology, and to analyse large datasets of genetic data to gain insights into the origins and mode of spread of key viral pathogens with significant public health impact.